R4ALZ PROJECT – a tool used for the assessment of cognitive control abilities
Nowadays, there are many neuropsychological tests to discriminate between cognitively healthy older adults, Subjective Cognitive Impairment (SCI), Mild Cognitive Impairment (MCI) and Dementia. However, these tests are usually affected by a persons’ educational level and for this reason, are not very sensitive. Cognitive control abilities such as inhibition and working memory are correlated with cognitive decline and dementia. As a result, it is essential to design new batteries, which will evaluate the abilities of cognitive control. It is also important these batteries not to require language skills, in order to minimize the influence of the patient’s educational level.
The R4Alz (REMEDES for Alzheimer) battery is a neuropsychological tool used for the assessment of cognitive control abilities. The battery comprises 3 different aspects of cognitive control (working memory, attention control, and executive function). The first subtests are assessing abilities such as working memory storage, working memory processing, working memory updating, while the next subtests are assessing attentional control abilities and specifically visual selective attention, sustained attention and divided attention. The last subtests are assessing inhibition, switching of attention, and cognitive flexibility. Every task includes 7 pads. Every pad is followed by a specific color, sound or figure depending on the task. The subtest’s instructions are both verbal and no verbal (sketches). The battery ‘s duration is almost an hour, while it’s administration is quite simple.
The validation study is in progress and the pilot results will be announced very soon. For participating in the validation study please contact the Greek Association of Alzheimer Disease and Related Disorders (Alzheimer Hellas) in Thessaloniki via:
- Visiting us in Petrou Sindika 13, Thessaloniki
- Calling us at 2310 810 411 (internal line 34)
- Sending a mail at firstname.lastname@example.org
- Poptsi, Eleni, Despina Moraitou, Emmanouil Tsardoulias, Andreas L. Symeonidis, and Magda Tsolaki (2020). “Is the Discrimination of Subjective Cognitive Decline from Cognitively Healthy Adulthood and Mild Cognitive Impairment Possible? A Pilot Study Utilizing the R4Alz Battery.” Journal of Alzheimer’s Disease Preprint: 1-18.
- Poptsi E, Tsardoulias E, Moraitou D, Symeonidis A, Tsolaki M (2019) REMEDES for Alzheimer-R4Alz Battery: Design and Development of a New Tool of Cognitive Control Assessment for the Diagnosis of Minor and Major Neurocognitive Disorders. Journal of Alzheimer’s Disease 72, 783-801.
- Eleni Poptsi, Despoina Moraitou, Tsardoulias Emmanouil, Panayiotou Konstantinos, Symeonidis Andreas,Petrou Loukas and Magda Tsolaki, “Αξιολόγηση του νοητικού ελέγχου στη γήρανση με τη χρήση ηλεκτρονικών εργα-λείων μέσω του συστήματος αντανακλαστικών/αντίδρασης REMEDES4Alzheimer“, 11th Panhellenic Conference on Alzheimer’s Disease & 3rdMediterranean Conference on Neurodegenerative Diseases PICAD & MeCoND, Thessaloniki,Greece, (2019)
- Eleni Poptsi, Despoina Moraitou, Tsardoulias Emmanouil, PanayiotouKonstantinos, Symeonidis Andreas, Petrou Loukas and Magda Tsolaki, “Συστοιχία REMEDES: Ένα νέο ηλεκτρονικό εργαλείο αξιολόγησης ικανοτήτων νοητι-κού ελέγχου στη γήρανση“, 11th Panhellenic Conferenceon Alzheimer’s Disease & 3rd Mediterranean Conference on Neurodegenerative Diseases PICAD& MeCoND, Thessaloniki, Greece, (2019)
- Tsardoulias Emmanouil, Panayiotou Konstantinos,Symeonidis Andreas and Petrou Loukas, “REMEDES: Τεχνικά χαρακτηριστικά και προδιαγραφές συστήματος αποτίμησης κιναισθησίας προς διάγνωση της νόσου Alzheimer“, 11th Panhellenic Conference on Alzheimer’s Disease &3rd Mediterranean Conference on Neurodegenerative Diseases PICAD & MeCoND, Thessaloniki,Greece, (2019)
R4Alz is the result of the active collaboration of
- Laboratory of Psychology, Section of Cognitive and Experimental Psychology, Faculty of Philosophy, School of Psychology, Aristotle University of Thessaloniki (AUTh), Greece
- Lab of Neurodegenerative Diseases, Center for Interdisciplinary Research and Innovation, Aristotle University of Thessaloniki (LND, CIRI – AUTh), Greece
- Greek Association of Alzheimer’s Disease and Related Disorders (GAADRD), Thessaloniki, Greece
- R4A group, School of Electrical and Computer Engineering, Faculty of Engineering, Aristotle University of Thessaloniki (AUTh), Greece
- 1st Department of Neurology, School of Medicine, Aristotle University of Thessaloniki (AUTh), Greece